Biomedicines, Free Full-Text
Por um escritor misterioso
Descrição
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated in the pathogenesis of various brain diseases, including neurodegenerative disorders, stroke, and psychiatric illnesses. This review paper provides a comprehensive overview of the intricate relationship between mitochondria and brain disease, focusing on the underlying pathological mechanisms and exploring potential therapeutic opportunities. The review covers key topics such as mitochondrial DNA mutations, impaired oxidative phosphorylation, mitochondrial dynamics, calcium dysregulation, and reactive oxygen species generation in the context of brain disease. Additionally, it discusses emerging strategies targeting mitochondrial dysfunction, including mitochondrial protective agents, metabolic modulators, and gene therapy approaches. By critically analysing the existing literature and recent advancements, this review aims to enhance our understanding of the multifaceted role of mitochondria in brain disease and shed light on novel therapeutic interventions.
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
Gut microbiota and its metabolites in depression: from pathogenesis to treatment - eBioMedicine
Generate Biomedicines Company Profile: Valuation, Funding & Investors
Biomedicines, Free Full-Text
Principle Component Analysis Of Liver Lipid Profile Fatty Acid
Computer Methods and Programs in Biomedicine, Journal
Frontiers Virus-Like Particles: Revolutionary Platforms for Developing Vaccines Against Emerging Infectious Diseases
Applied Sciences Free Full-Text Machine Learning Approach, 52% OFF
Biomedicines An Open Access Journal from MDPI
Long COVID: pathophysiological factors and abnormalities of coagulation: Trends in Endocrinology & Metabolism
Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality—Brief Report
de
por adulto (o preço varia de acordo com o tamanho do grupo)